Research Focus

Quantitative Proteomics & Cancer Biomarker Development

The Clinical Proteomics Laboratory aims to contribute to the proper management of cancer. Using quantitative proteomics, the Lab can identify candidate proteins that can be applied as biomarkers for diagnosis, prognosis, and treatment monitoring, and can be used as drug targets for identification of new treatment strategies. Our research includes the analysis of molecular mechanisms, and regulatory pathways to reveal critical processes involved in acquired and intrinsic drug resistance, and metastatic transformation. The Lab, together with collaborators from the National Institute of Molecular Biology and Biotechnology, Institute of Chemistry Academia Sinica, and Lung Center of the Philippines established the workflow and facility equipped for quantitative proteomics. The established Proteomics Lab can extend its application to other cancer types or other diseases, and to other research fields with the aim to use the technique for improvement of health and safety in the community.