Monissa C. Paderes, PhD
Organic Chemistry
Associate Professor
Laboratory Manager, NMR Facility
Email: mcpaderes1@up.edu.ph
Office Room and Phone No.: T235, Local 3669
Lab Room and Phone No.: R319-320, Local 3684
Research Laboratory: Organic Synthesis and Supramolecular Chemistry Lab (OSSChem Lab)
Education & Background
| Undergraduate | BS Chemistry, UP Diliman, 2001 |
| Graduate | PhD Chemistry, University at Buffalo, State University of New York, 2012 MS Chemistry, University of South Carolina, Columbia 2006 |
| Postdoctoral Training | Research Fellow, National University of Singapore, 2013-2014 |
| Previous Employment & Appointments | DDRE, Institute of Chemistry, UP Diliman, 2022-2023 Marie Curie Research Scientist, KU Leuven and Procter & Gamble, Belgium, 2014-2016 |
Teaching
| Chem 31: Elementary Organic Chemistry |
| Chem 33: Fundamentals of Organic Chemistry |
| Chem 34: Organic Reactions and Spectroscopy |
| Chem 230: Physical Organic Chemistry |
| Chem 236: Advanced Organic Synthesis |
| Chem 238: Heterocyclic Chemistry |
Research
Research Focus
Organic Synthesis and Supramolecular Chemistry
The OSSChem Laboratory aims to design and build molecular structures with unique and interesting properties suitable for medical and materials science applications. Key objectives include (1) the rational design and synthesis of organic compounds with biological significance (i.e. anticancer, antiviral), (2) construction of bis-urea-based supramolecular architectures as rheology modifiers for industrial products, and (3) development and fabrication of functional materials based on anthracene-containing polymeric compounds.
Selected Publications
(1) R. D. Hernandez, F. A. F. Genio, J. R. Casanova, M. T. Conato, M. C. Paderes. Antiproliferative activities and SwissADME predictions of physicochemical properties of carbonyl group-modified rotenone analogues. ChemistryOpen 2024, 13, e202300087. https://doi.org/10.1002/open.202300087
(2) J. A. P. Francisco, M. C. Paderes. Inhibitory effects of B-, C-, and E-Ring truncated deguelin derivatives against A549, HCT116, and MCF-7 cancer cells. ACS Omega 2023, 8, 43109-43117. https://doi.org/10.1021/acsomega.3c06619
(3) K. D. C. Magdato, M. C. Paderes. Gelation properties of amino-acid-based bis-urea compounds in organic solvents and in the presence of surfactants. Soft Mater. 2023, 21, 251-260. https://doi.org/10.1080/1539445X.2023.2222388
(4) M. C. Paderes; M. J. Diaz; C. A. Pagtalunan; D. W. Bruzon; G. A. Tapang. Photo-Controlled [4+4] Cycloaddition of Anthryl-Polymer Systems: A Versatile Approach to Fabricate Functional Materials. Chem. Asian J. 2022, 17, e202200193. https://doi.org/10.1002/asia.202200193
(5) F. A. F. Genio; M. C. Paderes. Functional Supramolecular Gels Comprised of Bis-Urea Compounds and Cosmetic Solvents. ChemSelect, 2021, 6, 7906-7911. https://doi.org/10.1002/slct.202102367
Awards & Extension Work
| UP Professorial Chairs, Faculty Grants, and IPAs 2022-2024: One UP Faculty Grant Award 2022, 2021: UP Diliman Centennial Professorial Chair 2023, 2017-2020: UP Diliman Centennial Faculty Grant 2021: Dr. Barker H. Brown Professorial Chair (UP Diliman) 2018, 2017: Ludovico & Elizabeth Llames Professorial Chair in Chemistry (UP Diliman) 2018-2024: UP International Publication Award |
| Awards of Thesis Advisees 2023: Leticia Shahani Award for Best Undergraduate Thesis in Chemistry – Judelyn F. Lacosta (BS Chemistry) 2021: Leticia Shahani Award for Best Undergraduate Thesis in Chemistry – Jaica Lynelle G. Paras (BS Chemistry) |